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The major focus of our research is to elucidate the mechanisms by which oxidative stress affects cardiovascular function.

My research interests focus on understanding the role of sterol/lipid binding proteins in in cholesterol and bile acid homeostasis in normal and disease states; e.g. diabetic nephropathy, NAFLD, and cholestasis.

My research focuses on the metabolic underpinnings of cardiovascular health and disease. This involves the critical examination of glycolysis, mitochondria, and other pathways of intermediary metabolism and the development of causal relationships between metabolic defects or signatures and cardiovascular (patho)physiology.

Dr. Clem’s laboratory focuses on understanding the molecular mechanisms that drive metabolic alterations in cancer.

Our goal is to provide insight into the ethanol-sensitive genes that regulate craniofacial development and lay the groundwork into the mechanistic basis of ethanol teratogenesis.

Dr. Klinge’s research focuses on the molecular mechanisms accounting for acquired endocrine resistance in breast cancer and the role of sex in mitigating the development of non-alcoholic fatty liver disease (NAFLD) in response to environmental pollutants and high fat diet.

I am a geneticist with broad interests in molecular, population, and evolutionary genetics as applied to human and animal model systems.

The Samuelson lab research interest is breast cancer genetics and prevention.

We are interested in defining diagnostic makers and molecular mechanisms for immune-mediated kidney diseases.

One of the essential keystones for the existence of life rests in the intricate relationship between biomolecular function, structure, and their dynamics.

Douglas Borchman’s research is focused on ophthalmology and visual sciences, where his team recently characterized changes in human lens lipid composition with regard to age and cataract.

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My group uses integrative structural biology with numerous computational techniques and biophysical approaches aimed at understanding macromolecular interactions and drug discovery.

Dr. Moore’s research interests are broadly centered around extracellular matrix (ECM) biology and its role in cardiac development, homeostasis & disease, and cell therapy-mediated cardiac repair.

My research is focused on the role of redox signaling in oxidative cardiac injury and heart disease.

The focus of my research is to understand how the immune system governs the pathophysiology of heart failure.

Dr. Cave is a physician-scientist spearheading research in environmental liver disease. His laboratory has multiple active and several pending NIH grants to support this research.

Dr. Smith's research is focused on utilizing cutting edge genomics technology to parse the complex host-pathogen relationship.

Dr. Hetman’s laboratory uses various molecular/cell neurobiology approaches to primarily address the regulation of neuronal gene expression programs and neuronal damage response, in conjunction with maladaptive changes in neural cells after traumatic spinal cord injury.

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My research regard retinal diseases and the molecular mechanisms of synapse formation in the retina.

Dr. Garbett applies biophysical approaches to the study of biomolecules and their interactions, with particular emphasis on the development of new technologies for medical diagnostics and drug development.

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The overarching theme of my group’s research is the development of novel and selective anticancer agents.